منابع مشابه
Features From “ Diphtheritic ” Poison to Molecular Toxinology
In his book The Sleepwalkers, Arthur Koestler commented on how scientific progress has evolved along much more irregular paths than generally realized. During the past 100 years, deciphering the pathogenic effects of microorganisms and discovering the many important bacterial toxins represent another case Koestler might have drawn. Some of the most important achievements in the loo-year story o...
متن کاملFrom fish poison to merck picrotoxin.
without loss of opioid analgesia. Clin Pharmacol Ther 2010; 87:204–11 5. Dahan A, Aarts L, smith TW: Incidence, reversal, and prevention of opioid-induced respiratory depression. ANEsThEsIoLogy 2010; 112:226–38 6. Boom M, Niesters M, sarton E, Aarts L, smith TW, Dahan A: Non-analgesic effects of opioids: opioid-induced respiratory depression. Curr Pharm Des 2012; 18:5994– 6004 7. okie s: A floo...
متن کاملSearching for a Poison in a Poison
chlorinated biphenyl (PC8I mixtures had been described previously. High mortality, liver damage, and edema were associated with only two of the three PCB5. Using column and gas chromatography, several compounds were identified in the diethylether fracdon of these two PCBs. A chick embryo assay confirmed the high toxicity of this fraction. Mass spectremetric and microcoulometric analyses indicat...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology and Chemotherapy
سال: 1953
ISSN: 0366-0826
DOI: 10.1111/j.1476-5381.1953.tb01345.x